Kidney Organoids | Renal Organoids | Corning

There are several protocols used to generate kidney organoids starting from human pluripotent stem cells (hPSCs). One method was demonstrated by Dr. Melissa H. Little’s lab in 2015. Here, researchers start with hPSCs seeded on cultureware coated withCorning® Matrigel® Matrixthrough various induction stages to intermediate mesoderm. For 3D culture, these cells are then transferred toTranswell® Permeable Supportswhere they mature into kidney organoids in appropriate differentiation conditions.Read moreabout this research and see other kidney organoid research examples below.

Discover how researchers were able to generate a self-organizing kidney by directing human embryonic stem cell differentiation towards a renal lineage.